Mio is a caring mother and she even willingly to donate some of her skin to Black Jack.
Mio and Black Jack are at the beach when her son went to investigate a mysterious, shiny looking object, half buried in the sand which reveals to be a bomb implanted by an evil gang. She and her son were badly injured due to the explosion and was rushed to a nearby hospital.
She loses all of her limbs and was slipped in a coma. Before she dies, she asks Black Jack to forgive his father for she knows the reason why her husband left them.
Mio was a beautiful women with shoulder length brown hair, long eyelashes, thin eyebrows, gray eyes. She wears a green long sleeve shirt, and a green knee length skirt. She also wore a gray necklace with a blue background color and a gray dove.